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LAIDLAW LAB

Located within the Brigham and Women’s Hospital and Harvard Medical School, the Laidlaw Lab is home to a team of talented physicians and scientists from diverse backgrounds. Researchers investigate a variety of inflammation and allergy-related topics using human respiratory tissues, translational research, and clinical trials. Research is conducted in a collaborative environment, benefitting the training of everyone involved, from Research Assistants to Physician-Scientists, and Post-Doctoral Fellows. Outside of the research directly conducted by individual teams, trainees are exposed to other ongoing research projects in the division and throughout the institution. Opportunities include:

  • The Jeff and Penny Vinik Center for Translational Immunology is housed within the BWH Division of Allergy and Clinical Immunology and led by the Division Chief, Dr. Joshua Boyce. The mission of the Center is to support early-stage groundbreaking research into the immunopathologic basis of human disease, to train the next generation of immunologists and prepare them for independent careers in research, and to train and support the career development of academic physician-scientists in the field of Allergy and Immunology
  • The Brigham Asthma Collaborative Research Group is a group of immunologists, airway biologists and researchers pursuing genomics, metabolomics, database research, and clinical trials, who share and facilitate research on asthma.
  • ImmGen is a consortium of immunologists and computational biologists dedicated to understanding gene expression and regulation underlying immunity.
  • The Brigham Research Institute Lung Center is designed to enhance, synergize, and stimulate interdepartmental and individual research programs on lung disease across the hospital.
  • The Severe Asthma Program, part of the Partners Asthma Center, brings together a team of allergists and pulmonologists who work in collaboration with specialists in Otolaryngology, Gastroenterology, and Psychiatry to help manage patients whose asthma has been difficult to control with conventional therapy.
  • The Multidisciplinary Sinus Team is a group of sinus disease experts from the Divisions of Allergy & Clinical Immunology and Otolaryngology who collaborate on clinical care teams and work together through ongoing sinus-related research projects.

We are located in state-of-the-art laboratory facilities on the 5th floor of the BWH Hale Building for Transformative Medicine. The floor is home to the Inflammation and Allergic Disease Research Section within the Division of Allergy and Clinical Immunology. Some of the research conducted in the division includes mechanisms of inflammation, eicosanoid biology, mast cell biology, immunoregulation, mucosal and lymphocyte biology, chemosensory and smell disorders investigation, genomic medicine, clinical trials, and population research. The building houses cutting edge technologies that allow us to perform ELISAs, flow cytometry, flow cytometric cell sorting, tissue digestion for single-cell suspension, human cell culture, single cell RNAseq and more. Additionally, our collaborations with other researchers in the Boston area broadens the scope of techniques and technology available to us.

Trainees, junior investigators, and seasoned researchers enjoy a highly collaborative environment including joint research seminars and journal clubs. There are many excellent opportunities to attend seminar series and presentations from experts in various fields, including the Wednesday Immunology Seminar Series, hosted by the Harvard Medical School Committee on Immunology.

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